Cover Image: Human neurons differentiated from induced pluripotent stem cells (iPSC) reveal the complex cellular architecture achievable in modern disease modeling platforms. This fluorescence micrograph captures mature neurons (red, β3-tubulin) and GABAergic interneurons (green, GABA receptor) derived from a patient with familial Alzheimer's disease, illustrating the sophisticated cell types now routinely generated for neuropsychiatric research. Such advances underscore the importance of establishing rigorous validity standards for iPSC models, as discussed by Kolsters et al. in this issue (pages 27–33).

Image credit: Morozless/Wikimedia Commons, CC BY-SA 4.0. Originally submitted to Science Photo Competition 2023 in Ukraine.

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Article Contents

Table of Contents

Cover Art

Najaf Amin: Rare coding genetic variation and downstream omics hold the key to understanding the pathogenesis of depression

Cardiac rhythms as windows into brain stimulation response: Promise and pitfalls in precision psychiatry

Psychedelics in the context of stress and psychiatric disorders: A new horizon in mental health treatment

Heart rate modulation and clinical improvement in major depression: A randomized clinical trial with accelerated intermittent theta burst stimulation

Bruce M. Cohen: An eclectic life and a multidisciplinary approach to the complex determinants and diverse presentations of psychiatric disorders

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